1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. CAY10701

CAY10701 (Compound 20) is a 7-deazahypoxanthine analogue with anticancer activity.

For research use only. We do not sell to patients.

CAY10701

CAY10701 Chemical Structure

CAS No. : 1616967-52-2

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Description

CAY10701 (Compound 20) is a 7-deazahypoxanthine analogue with anticancer activity[1].

Cellular Effect
Cell Line Type Value Description References
HeLa GI50
0.022 μM
Compound: 1
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 38865195]
HeLa GI50
0.22 μM
Compound: 7
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
[PMID: 26641132]
MCF7 GI50
0.038 μM
Compound: 7
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 26641132]
RKO GI50
0.009 μM
Compound: 7
Antiproliferative activity against human RKO cells after 72 hrs by SRB assay
Antiproliferative activity against human RKO cells after 72 hrs by SRB assay
[PMID: 26641132]
SK-CO-1 GI50
0.17 μM
Compound: 7
Antiproliferative activity against human SKCO1 cells after 72 hrs by SRB assay
Antiproliferative activity against human SKCO1 cells after 72 hrs by SRB assay
[PMID: 26641132]
SW-620 GI50
0.011 μM
Compound: 7
Antiproliferative activity against human SW620 cells after 72 hrs by SRB assay
Antiproliferative activity against human SW620 cells after 72 hrs by SRB assay
[PMID: 26641132]
SW48 GI50
0.012 μM
Compound: 7
Antiproliferative activity against human SW48 cells after 72 hrs by SRB assay
Antiproliferative activity against human SW48 cells after 72 hrs by SRB assay
[PMID: 26641132]
WI-38 GI50
25.4 μM
Compound: 7
Antiproliferative activity against human WI38 cells after 72 hrs by SRB assay
Antiproliferative activity against human WI38 cells after 72 hrs by SRB assay
[PMID: 26641132]
In Vitro

CAY10701 (Compound 20) (48 h) inhibits cell proliferation in HeLa and MCF cells with IC50 values of 12.4 μM and 58.8 μM, respectively [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

381.43

Formula

C24H19N3O2

CAS No.
SMILES

O=C1C2=C(NC(CCCC#C)=N1)NC(C(C3=CC=CC=C3)=O)=C2C4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CAY10701
Cat. No.:
HY-121092
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