Cbz-NH-PEG1-CH2CH2COOH
Based on 1 Customer Validation
Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.80%
- CAS No.: 1205751-19-4
- Formula: C13H17NO5
- Molecular Weight:267.28
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1205751-19-4
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Appearance Solid
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Molecular Weight 267.28
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Formula C13H17NO5
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Color White to off-white
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SMILES
O=C(O)CCOCCNC(OCC1=CC=CC=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (374.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7414 mL | 18.7069 mL | 37.4138 mL | 93.5345 mL |
| 5 mM | 0.7483 mL | 3.7414 mL | 7.4828 mL | 18.7069 mL | |
| 10 mM | 0.3741 mL | 1.8707 mL | 3.7414 mL | 9.3535 mL | |
| 15 mM | 0.2494 mL | 1.2471 mL | 2.4943 mL | 6.2356 mL | |
| 20 mM | 0.1871 mL | 0.9353 mL | 1.8707 mL | 4.6767 mL | |
| 25 mM | 0.1497 mL | 0.7483 mL | 1.4966 mL | 3.7414 mL | |
| 30 mM | 0.1247 mL | 0.6236 mL | 1.2471 mL | 3.1178 mL | |
| 40 mM | 0.0935 mL | 0.4677 mL | 0.9353 mL | 2.3384 mL | |
| 50 mM | 0.0748 mL | 0.3741 mL | 0.7483 mL | 1.8707 mL | |
| 60 mM | 0.0624 mL | 0.3118 mL | 0.6236 mL | 1.5589 mL | |
| 80 mM | 0.0468 mL | 0.2338 mL | 0.4677 mL | 1.1692 mL | |
| 100 mM | 0.0374 mL | 0.1871 mL | 0.3741 mL | 0.9353 mL |
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