CD38 inhibitor 1 (Standard)
CD38 inhibitor 1 (Standard) is the analytical standard of CD38 inhibitor 1 (HY-123999). This product is intended for research and analytical applications. CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38.
For research use only. We do not sell to patients.
- CAS No.: 1700637-55-3
- Formula: C22H27N3O3S
- Molecular Weight:413.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1700637-55-3
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Molecular Weight 413.53
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Formula C22H27N3O3S
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SMILES
O=C1N(C)C2=C(C=C(C3=CN=CS3)C=C2)C(N[C@H]4CC[C@H](OCCOC)CC4)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71. [Content Brief]
[2]. Tarragó MG, Chini CCS, Kanamori KS, et al. A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline. Cell Metab. 2018;27(5):1081-1095.e10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)