CFM 1571 hydrochloride (Standard)
CFM 1571 hydrochloride (Standard) is the analytical standard of CFM 1571 (hydrochloride) (HY-107546). This product is intended for research and analytical applications. CFM 1571 hydrochloride is the stimulator of the nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC50 and IC50 of 5.49 μM and 2.84 μM, respectively. Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). CFM 1571 hydrochloride has the potential for the research of cardiovascular and other diseases.
For research use only. We do not sell to patients.
- CAS No.: 1215548-30-3
- Formula: C23H29ClN4O3
- Molecular Weight:444.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1215548-30-3
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Molecular Weight 444.95
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Formula C23H29ClN4O3
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SMILES
O=C(C1=CC(OCCCN(C)C)=NN1CC2=CC=CC=C2)NC3=CC=C(C=C3)OC.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Selwood DL, et al. Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase. J Med Chem. 2001;44(1):78-93. [Content Brief]
[2]. Evgenov OV, et al. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat Rev Drug Discov. 2006;5(9):755-768. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)