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Art. -Nr.: HY-129648

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AC-7954 free base

AC-7954 free base is a selective nonpeptidic urotensin receptor agonist (EC₅₀: 300 nM at the human UII receptor).

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CAS. Nr.: 734528-95-1
Formel: C₁₉H₂₀ClNO₂
Molecular Weight:329.82

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

AC-7954 free base Chemical Structure

CAS. Nr.: 734528-95-1

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

AC-7954 free base is a selective nonpeptidic urotensin receptor agonist (EC₅₀: 300 nM at the human UII receptor)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	250 nM Compound: 8a, AC-7954, enantiomer	Agonist activity at human urotensin 2 expressed in CHO cells by FLIPR Agonist activity at human urotensin 2 expressed in CHO cells by FLIPR	[PMID: 20043680]

Chemical Information

CAS. Nr. 734528-95-1
Molecular Weight 329.82
Formel C₁₉H₂₀ClNO₂
SMILES

O=C1OC(CC2=C1C=CC=C2)(CCN(C)C)C3=CC=C(C=C3)Cl
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Croston GE, et al. Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954). J Med Chem. 2002 Nov 7;45(23):4950-3. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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