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Agazisiran

Agazisiran, a siRNA,is a complement factor B synthesis reducer.

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  • CAS. Nr.: 2985646-78-2
  • Formel: C534H706F15N179O329P44S8
  • Molecular Weight:16800.60
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Agazisiran Chemical Structure
    Agazisiran Chemical Structure
CAS. Nr.: 2985646-78-2
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  • Agazisiran Chemical Structure
    Agazisiran Chemical Structure RNA, ([3'-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2'-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]]U-(5'→5')-sp-Gm-sp-Gm-Am-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-Gm-Gm-Am-Um-Gm-Um-Cm-Um-sp-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]A), complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Gm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)C-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)U-sp-Cm-sp-Cm) (1:1)
    1/16
  • RNA, ([3'-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2'-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]]U-(5'→5')-sp-Gm-sp-Gm-Am-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-Gm-Gm-Am-Um-Gm-Um-Cm-Um-sp-Am-(3'→3')-sp-[1'-de(6-amino-9H-purin-9-yl)]A), complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Gm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)C-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)U-sp-Cm-sp-Cm) (1:1)