Antibacterial agent 301
Antibacterial agent 301 (compound 14c) is a pyridine-amide pleuromutilin derivative with broad-spectrum antibacterial and pronounced antimycoplasmal activity. Antibacterial agent 301 inhibits peptidyl transferase center (PTC), breaks down biofilms, and disrupts cell membranes in multidrug-resistant (MDR) bacteria. Antibacterial agent 301 exhibits activity in a systemic methicillin-resistant Staphylococcus aureus (MRSA) infection mouse model. Antibacterial agent 301 can be used for MDR bacterial infection research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C33H49N3O5S
- Molecular Weight:599.82
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
| Species | Dose | Route | T1/2 | Tmax | Cmax | AUCinf | Vz-F_obs | ClF_obs | MRTlast |
|---|---|---|---|---|---|---|---|---|---|
| Rat[1] | 1 mg/kg | i.v. | 0.47 h | 0.03 h | 8243 ng/mL | 3448 ng·h/mL | 198.8 mL/kg | 290.45 mL/h/kg | 0.5 h |
Chemical Information
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Molecular Weight 599.82
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Formel C33H49N3O5S
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SMILES
O=C(O[C@@H]1C[C@](C=C)(C)[C@@H](O)[C@H](C)[C@]2(CCC3=O)[C@]3([H])[C@@]1(C)[C@H](C)CC2)CSC4=C(NC([C@@H](N)CC(C)C)=O)C=NC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Antibacterial agent 301 Related Classifications
HY-179405 Related Classifications
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