CB-25
Based on 1 Customer Validation
CB-25 is a ligand of CB1 cannabinoid receptors, acting as a partial agonist. CB-25 enhances Forskolin (HY-15371)-induced cAMP formation in cancer cells but not hCB1-CHO cells.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.84%
- CAS. Nr.: 869376-63-6
- Formel: C25H41NO3
- Molecular Weight:403.60
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-2H3 | IC50 |
17 μM
Compound: 25
|
Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake
Inhibition of anandamide membrane transporter in RBL-2H3 cells assessed as [14C]anandamide uptake
|
[PMID: 16279794] |
Chemical Information
-
CAS. Nr. 869376-63-6
-
Appearance Solid
-
Molecular Weight 403.60
-
Formel C25H41NO3
-
Color White to off-white
-
SMILES
O=C(NC1CC1)CCCCCCCCCCOC2=CC(CCCCC)=CC(O)=C2
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : ≥ 100 mg/mL (247.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (263 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4777 mL | 12.3885 mL | 24.7770 mL | 61.9425 mL |
| 5 mM | 0.4955 mL | 2.4777 mL | 4.9554 mL | 12.3885 mL | |
| 10 mM | 0.2478 mL | 1.2389 mL | 2.4777 mL | 6.1943 mL | |
| 15 mM | 0.1652 mL | 0.8259 mL | 1.6518 mL | 4.1295 mL | |
| 20 mM | 0.1239 mL | 0.6194 mL | 1.2389 mL | 3.0971 mL | |
| 25 mM | 0.0991 mL | 0.4955 mL | 0.9911 mL | 2.4777 mL | |
| 30 mM | 0.0826 mL | 0.4130 mL | 0.8259 mL | 2.0648 mL | |
| 40 mM | 0.0619 mL | 0.3097 mL | 0.6194 mL | 1.5486 mL | |
| 50 mM | 0.0496 mL | 0.2478 mL | 0.4955 mL | 1.2389 mL | |
| 60 mM | 0.0413 mL | 0.2065 mL | 0.4130 mL | 1.0324 mL | |
| 80 mM | 0.0310 mL | 0.1549 mL | 0.3097 mL | 0.7743 mL | |
| 100 mM | 0.0248 mL | 0.1239 mL | 0.2478 mL | 0.6194 mL |