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Enoblituzumab

(Synonyms: MGA271)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Enoblituzumab (MGA271) is a humanized IgG1κ monoclonal antibody recognizing human B7-H3 protein, a member of the B7 family of immune regulators.

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  • Reinheit : 99.16%
  • CAS. Nr.: 1353485-38-7
  • Molecular Weight:146.1 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Enoblituzumab
  • Experimental Validation Results for Enoblituzumab
  • Experimental Validation Results for Enoblituzumab
  • Experimental Validation Results for Enoblituzumab
  • Enoblituzumab Chemical Structure
    Enoblituzumab Chemical Structure
CAS. Nr.: 1353485-38-7
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Enoblituzumab Product Recommendations:

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD276/B7-H3 Protein, Human can bind Enoblituzumab. The EC50 for this effect is 2.502 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 MCF-7 cells with Enoblituzumab (HY-P9966, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Loaded Enoblituzumab on Protein A Chip, can bind CD276/B7-H3 Protein, Human (HEK293, His, HY-P7327) with an affinity constant of 1.27E-07 M as determined in SPR assay.

  • Enoblituzumab Chemical Structure
    1/16
  • Enoblituzumab
  • Immobilized CD276/B7-H3 Protein, Human can bind Enoblituzumab. The EC50 for this effect is 2.502 ng/mL.
  • Flow cytometric analysis of 1X106 MCF-7 cells with Enoblituzumab (HY-P9966, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Loaded Enoblituzumab on Protein A Chip, can bind CD276/B7-H3 Protein, Human (HEK293, His, HY-P7327) with an affinity constant of 1.27E-07 M as determined in SPR assay.