Falecalcitriol
Based on 1 Customer Validation
Falecalcitriol(Fulstan; Hornel) is an analog of calcitriol; has a higher potency both in vivo and in vitro systems, and longer duration of action in vivo.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.90%
- CAS. Nr.: 83805-11-2
- Formel: C27H38F6O3
- Molecular Weight:524.58
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Speicherung:
4°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 83805-11-2
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Appearance Solid
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Molecular Weight 524.58
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Formel C27H38F6O3
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Color White to off-white
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SMILES
C[C@]([C@]/12[H])([C@H](CC2)[C@@H](CCCC(C(F)(F)F)(C(F)(F)F)O)C)CCCC1=C/C=C(C[C@@H](O)C[C@@H]3O)\C3=C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (190.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Ito H, Ogata H, Yamamoto M, Takahashi K, Shishido K, Takahashi J, Taguchi S, Kinugasa E. Comparison of oral falecalcitriol and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism: a randomized, crossover trial. Clin Nephrol. 2009 Jun;71(6):660-8. [Content Brief]
[2]. Tokunaga M, Tamura M, Kabashima N, Serino R, Shibata T, Matsumoto M, Miyamoto T, Miyazaki M, Furuno Y, Takeuchi M, Abe H, Okazaki M, Otsuji Y. Falecalcitriol for conventional vitamin D therapy-resistant secondary hyperparathyroidism in a continuous ambulatory peritoneal dialysis patient. Clin Nephrol. 2008 May;69(5):393-4. [Content Brief]
[3]. Iwao Y, Yamaguchi Y, Fujii K, Toba Y, Asada M, Nagano N, Yamamoto H, Hyoma K, Yamada S, Hirano H, Tone Y, Ohtani H, Saika Y, Fujii R. Long-term suppressive effect of falecalcitriol on parathyroid hormone secretion in secondary hyperparathyroidism in hemodialysis patients.Clin Calcium. 2006 May;16(5):847-51. [Content Brief]
[4]. Morii H. Falecalcitriol as a new therapeutic agent for secondary hyperparathyroidismClin Calcium. 2005 Jan;15(1):29-33. [Content Brief]
[5]. Ohtsuka N, Urayama K. Pharmacological action and clinical effects of falecalcitriol, a highly potent derivative of active vitamin D3.Nihon Yakurigaku Zasshi. 2002 Dec;120(6):427-36. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9063 mL | 9.5314 mL | 19.0629 mL | 47.6572 mL |
| 5 mM | 0.3813 mL | 1.9063 mL | 3.8126 mL | 9.5314 mL | |
| 10 mM | 0.1906 mL | 0.9531 mL | 1.9063 mL | 4.7657 mL | |
| 15 mM | 0.1271 mL | 0.6354 mL | 1.2709 mL | 3.1771 mL | |
| 20 mM | 0.0953 mL | 0.4766 mL | 0.9531 mL | 2.3829 mL | |
| 25 mM | 0.0763 mL | 0.3813 mL | 0.7625 mL | 1.9063 mL | |
| 30 mM | 0.0635 mL | 0.3177 mL | 0.6354 mL | 1.5886 mL | |
| 40 mM | 0.0477 mL | 0.2383 mL | 0.4766 mL | 1.1914 mL | |
| 50 mM | 0.0381 mL | 0.1906 mL | 0.3813 mL | 0.9531 mL | |
| 60 mM | 0.0318 mL | 0.1589 mL | 0.3177 mL | 0.7943 mL | |
| 80 mM | 0.0238 mL | 0.1191 mL | 0.2383 mL | 0.5957 mL | |
| 100 mM | 0.0191 mL | 0.0953 mL | 0.1906 mL | 0.4766 mL |
Falecalcitriol Related Classifications
HY-32342 Related Classifications
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