FLT3-IN-38
FLT3-IN-38 (Flt-3 Inhibitor II) is a FLT3 inhibitor. FLT3-IN-38 has off-target effects and inhibits serine/threonine kinase haspin. Haspin is a mitotic signal coordinator. FLT3-IN-38 can be used for cancer research.
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- CAS. Nr.: 896138-40-2
- Formel: C17H12N2O3
- Molecular Weight:292.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| EOL1 | IC50 |
0.04 μM
Compound: 102
|
Inhibition of endogenous FLT3 in EOL1 cells
Inhibition of endogenous FLT3 in EOL1 cells
|
[PMID: 16722630] |
| K562 | IC50 |
4.2 μM
Compound: 102
|
Inhibition of oncogenic Bcr-Abl kinase in K562 cells
Inhibition of oncogenic Bcr-Abl kinase in K562 cells
|
[PMID: 16722630] |
Chemical Information
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CAS. Nr. 896138-40-2
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Molecular Weight 292.29
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Formel C17H12N2O3
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SMILES
O=C(C(N1)=CC2=C1C=CC(O)=C2)C(N3)=CC4=C3C=CC(O)=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)