Flunitrazolam
Flunitrazolam (FNTZ) is an orally active triazolobenzodiazepine designer benzodiazepine compound and a positive allosteric modulator of the GABAA receptor. Flunitrazolam undergoes biometabolic transformation, and 7-amino-flunitrazolam and 7-acetamido-flunitrazolam are its main detectable metabolites in urine. Flunitrazolam can be used in research related to GABA-mediated diseases, such as neurological disorders.
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- CAS. Nr.: 2243815-18-9
- Formel: C17H12FN5O2
- Molecular Weight:337.31
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
Beschreibung
In Vitro
Flunitrazolam (compound 36) acts as a positive allosteric modulator of α1β2γ2 GABAA receptors in CHO cells, and its activity depends on the classical BZD α+/γ2- binding pocket.[1]
Flunitrazolam (FNTZ) undergoes biotransformation, and 7-amino-FNTZ and 7-acetamido-FNTZ are its main detectable metabolites in urine; moreover, in human liver microsomes, 7-amino-FNTZ is the only metabolite of flunitrazolam produced under the study conditions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 2243815-18-9
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Appearance Solid
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Molecular Weight 337.31
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Formel C17H12FN5O2
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Color Light yellow to yellow
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SMILES
O=[N+](C1=CC=C(N2C(CN=C3C4=CC=CC=C4F)=NN=C2C)C3=C1)[O-]
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Synonyms
FNTZ
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (294 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)