FUT8-IN-1
FUT8-IN-1 (Compound 37) is an inhibitor for α-1,6-fucosyltransferase (FUT8) with an KD of 49 nM and an IC50 of ca. 50 µM. FUT8-IN-1 generates a highly active naphthoquinone imine intermediate in the presence of FUT8, and inhibits the enzymatic activity of FUT8.
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- CAS. Nr.: 3073704-71-6
- Formel: C23H25ClN2O
- Molecular Weight:380.91
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 3073704-71-6
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Molecular Weight 380.91
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Formel C23H25ClN2O
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SMILES
ClC1=CC=C2C(C=CC(O)=C2CN3CCN(CC)CC3C4=CC=CC=C4)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)