CCND2 - cyclin D2 Gene

Also Known as MPPH3; KIAK0002

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 894

About CCND2

Cytogenetic location: 12p13.32 Genomic coordinates (GRCh38): 12:4,273,762-4,305,353 (from NCBI)

This gene has 8 transcripts (splice variants), 287 orthologues, 18 paralogues and is associated with 81 phenotypes. Ubiquitous expression in adrenal (RPKM 22.1), heart (RPKM 18.6) and 24 other tissues.

Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]

CCND2 Products (1)

mRNA Protein Name
NM_001759.4 NP_001750.1 G1/S-specific cyclin-D2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables cyclin-dependent protein serine/threonine kinase activator activity IDA
IDA: Inferred from direct assay
18827403 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9840943 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
8114739 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in G1/S transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
18827403 GOA
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
24130168 GOA
involved in positive regulation of G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
24130168 GOA
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
24130168 GOA
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
8114739 GOA
involved in positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
8114739 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in chromatin IDA
IDA: Inferred from direct assay
18827403 GOA
part of cyclin D2-CDK4 complex IPI
IPI: Inferred from physical interaction
11896535 GOA
part of cyclin-dependent protein kinase holoenzyme complex IDA
IDA: Inferred from direct assay
8114739 GOA
located in cytosol IDA
IDA: Inferred from direct assay
18827403 GOA
located in nuclear membrane IDA
IDA: Inferred from direct assay
18827403 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
18827403 GOA
located in nucleus IDA
IDA: Inferred from direct assay
18827403 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCND2 Protein Structure

Cyclin_N

Cyclin_N: Cyclin, N-terminal domain (26 - 151)

Cyclin_C

Cyclin_C: Cyclin, C-terminal domain (154 - 264)

  • 0
  • 100
  • 200
  • 289 a.a.
Protein Preferred Names Protein Names

G1/S-specific cyclin-D2

CCND2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
BFG-2H
27107012
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
Validated Y2H
25416956
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
Validated Y2H
32296183
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
Y2H Array
25416956
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
Anti Tag CoIP
33961781
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
Anti Tag CoIP
28514442
Intra
CCND2 P30279 CDK5 Homo sapiens Q00535
Y2H
27107012
Intra
CCND2 P30279 CDK4 Homo sapiens P11802
SLC
27107012
Intra
CCND2 P30279 CDK4 Homo sapiens P11802
BFG-2H
27107012
Intra
CCND2 P30279 CDK4 Homo sapiens P11802
Y2H Array
31515488
Intra
CCND2 P30279 CDK4 Homo sapiens P11802
Y2H
27107012
Intra
CCND2 P30279 CDK4 Homo sapiens P11802
Anti Tag CoIP
33961781
Intra
CCND2 P30279 CDK4 Homo sapiens P11802
Anti Tag CoIP
28514442
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
BFG-2H
27107012
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Y2H Pooling
16189514
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Validated Y2H
25416956
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Validated Y2H
32296183
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Anti Tag CoIP
33961781
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Anti Tag CoIP
28514442
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Y2H Array
31515488
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
Y2H Prey Pooling
25416956
Intra
CCND2 P30279 CDKN1A Homo sapiens P38936
PLA
25241761
Intra
CCND2 P30279 CDK2 Homo sapiens P24941
Anti Tag CoIP
28514442
Intra
CCND2 P30279 CDK2 Homo sapiens P24941
Anti Tag CoIP
33961781
Intra
CCND2 P30279 CDK2 Homo sapiens P24941
Y2H
9840943
Intra
CCND2 P30279 CDKN1B Homo sapiens P46527
Y2H Pooling
16189514
Intra
CCND2 P30279 CDKN1B Homo sapiens P46527
Anti Tag CoIP
33961781
Intra
CCND2 P30279 CDKN1B Homo sapiens P46527
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CCND2 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P7773 CCND2 Protein, Human (His) P30279 (M1-L289) ≥ 95%, as determined by reducing SDS-PAGE.

CCND2 Antibodies

Art. -Nr. Produktname Anwendung Reactivity
HY-P80634 Cyclin D2/CCND2 Antibody (YA789) WB Human
HY-P85523 Cyclin D2/CCND2 Antibody (YA5215) WB Human

Related Diseases

Diseases Alias
Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 3

  • MPPH3

  • Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome, Type 3
Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1

  • Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome

  • Mpph Syndrome

  • Mpph

  • MPPH1

  • Meg-Pmg-Megacc Syndrome

  • Megalencephaly-Polymicrogyria-Postaxial Polydactyly-Hydrocephalus Syndrome

  • Megalencephaly, Polymicrogyria, Mega Corpus Callosum Syndrome

  • Megalencephaly, Mega Corpus Callosum, And Complete Lack Of Motor Development

  • Megalencephaly And Perisylvian Polymicrogyria With Postaxial Polydactyly And Hydrocephalus

  • Megalencephaly, Polymicrogyria, And Hydrocephalus Syndrome

  • Meg-Pmg-Poly-Hyd

  • Megalencephaly-Postaxial Polydactyly-Polymicrogyria-Hydrocephalus Syndrome

  • Megalencephaly Mega Corpus Callosum And Complete Lack Of Motor Development

  • Megalencephaly-Polymicrogyria-Mega Corpus Callosum Syndrome

  • Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome, Type 1

  • Megalanecephaly Polymicrogyria-Polydactyly Hydrocephalus Syndrome
Megalencephaly

  • Macroencephaly

  • Macrencephaly
Hydrocephalus

  • Hydrocephalus, Nonsyndromic, Autosomal Recessive

  • Hydrocephalus, X-Linked

  • Hydrocephalus Adverse Event

  • Hydrocephaly Nos
Polymicrogyria

  • Pmg
Polydactyly

  • Non-Syndromic Polydactyly

  • Polydactyly, Postaxial

  • Postaxial Polydactyly

  • Supernumerary Digit

  • Extra Digits

  • Hyperdactyly

  • Polydactylia

  • Polydactylism

  • Supernumerary Digits
Embryonal Carcinoma

  • Embryonal Neoplasm

  • Embryonal Cancer

  • Primary Extragonadal Embryonal Carcinoma

  • Embryo Neoplasm

  • Carcinoma Embryonal

  • Cancer Embryonal

  • Carcinoma, Embryonal

  • Extragonadal Embryonal Carcinoma

  • Cancer, Embryonal
Retinoblastoma

  • RB

  • Trilateral Retinoblastoma

  • RB1

  • Retinoblastoma, Trilateral

  • Neuroblastoma Of Retina

  • Rb - Retinoblastoma

  • Eye Cancer, Retinoblastoma

  • Retinal Cancer

  • Retinal Tumor

  • Glioma, Retinal

  • Non-Hereditary Retinoblastoma

  • Childhood Cancer Retinoblastoma

  • Malignant Neoplasm Of Retina

  • Retinal Neoplasms
Burkitt Lymphoma

  • Burkitt'S Lymphoma

  • BL

  • Burkitt Lymphoma, Somatic

  • Burkitt Lymphoma/Leukaemia

  • Burkitt'S Tumor

  • Burkitt'S Tumor Or Lymphoma

  • Malignant Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma

  • Burkitt Tumor

  • Burkitts Lymphoma

  • Lymphoma, Small Noncleaved-Cell

  • Burkitt Tumour

  • Diffuse Small Noncleaved Malignant Burkitt Lymphoma

  • Malignant Burkitt Lymphoma

  • “Burkitt-Like” Lymphoma

  • Undifferentiated Burkitt Lymphoma

  • Small Noncleaved Cell Burkitt Lymphoma
Mantle Cell Lymphoma

  • Lymphoma, Mantle Cell

  • Lcm

  • Mcl

  • Mantle Zone Lymphoma

  • Lymphoma Mantle-Cell

  • Lymphoma, Mantle-Cell

  • Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

  • Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

  • Diffuse Small Cleaved-Cell Lymphoma

  • Diffuse Small Cleaved Cell Malignant Lymphoma

  • Small Cleaved Cell Non-Hodgkin Lymphoma

  • Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

  • Malignant Lymphomatous Polyposis

  • Malignant Small Cell, Noncleaved, Diffuse Lymphoma

  • Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

  • Cleaved Cell Lymphoma

  • Small Cell Mantle Cell Lymphoma

  • Small Cleaved Cell Malignant Lymphoma
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
B-Cell Lymphoma

  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos
T-Cell Acute Lymphoblastic Leukemia

  • T-Cell Leukemia

  • Acute T Cell Leukemia

  • Precursor T Lymphoblastic Leukemia

  • Precursor T-Lymphoblastic Lymphoma/Leukemia

  • T Acute Lymphoblastic Leukemia

  • T-Cell Acute Lymphocytic Leukaemia

  • T-Cell Lymphoblastic Leukemia/Lymphoma

  • Leukemia T-Cell

  • Leukemia, T-Cell

  • Leukemia, Acute, Lymphoblastic, T-Cell

  • Leukemia, T-Cell Acute Lymphoblastic

  • Leukemia, Acute T-Cell

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

  • Precursor T-Cell Lymphoblastic Lymphoma

  • Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Seminoma

  • Seminoma, Pure
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Lymphoma

  • Lymphoid Cancer

  • Lymphomas

  • Lymphoid Cancers

  • Lymphoid Neoplasm

  • Lymphoma Nos

  • Nhl - [Non-Hodgkin Lymphoma]

  • Non-Hodgkin Lymphoma

  • Non-Hodgkin Lymphoma, Nos

  • Non-Hodgkin Malignant Lymphoma Nos
Rhabdomyosarcoma
Glioblastoma

  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Myeloma, Multiple

  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]
Leukemia, Chronic Lymphocytic

  • Chronic Lymphocytic Leukemia

  • B-Cell Chronic Lymphocytic Leukemia

  • CLL

  • B-Cell Chronic Lymphoid Leukemia

  • Chronic Lymphatic Leukemia

  • Chronic Lymphocytic Leukaemia

  • Lymphoplasmacytic Leukemia

  • Small Lymphocytic Lymphoma

  • Leukemia, Chronic Lymphatic

  • B-Cell Chronic Lymphocytic Leukaemia

  • Chronic Lymphatic Leukaemia

  • Lymphoplasmacytic Leukaemia

  • B Cell Chronic Lymphocytic Leukemia

  • Chronic B-Cell Lymphocytic Leukemia

  • Leukemia, Lymphocytic, Chronic

  • B-Cll

  • Chronic Lymphoid Leukemia

  • Leukemia Lymphocytic Chronic

  • Lymphoma Small Lymphocytic

  • Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, Non-Hodgkin, Familial

  • Non-Hodgkin Lymphoma

  • Lymphoma, Non-Hodgkin

  • NHL

  • Lymphoma, Non-Hodgkin, Somatic

  • Lymphoma, Follicular, Somatic

  • Familial Non-Hodgkin Lymphoma

  • Lymphoma Non-Hodgkins

  • Follicular Lymphoma, Somatic

  • Lymphosarcoma

  • Non-Hodgkins Lymphoma
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Anaplastic Astrocytoma

  • Grade Iii Astrocytoma

  • Astrocytoma, Anaplastic

  • Grade Iii Astrocytic Tumor
Polymicrogyria, Bilateral Perisylvian, X-Linked

  • Bilateral Perisylvian Polymicrogyria

  • Polymicrogyria, Bilateral Perisylvian

  • Pmgx

  • Perisylvian Syndrome, Congenital Bilateral

  • Cbps

  • Congenital Bilateral Perisylvian Syndrome

  • Perisylvian Syndrome

  • BPPX

  • Bpp
Granulomatous Disease, Chronic, X-Linked

  • CGDX

  • Chronic Granulomatous Disease, X-Linked

  • X-Linked Chronic Granulomatous Disease

  • Cgd

  • Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked

  • Cdgx

  • X-Linked Chronic Cytochrome B-Negative Granulomatous Disease

  • Chronic Granulomatous Disease Cytochrome B-Negative X-Linked

  • Chronic Granulomatous Disease Cytochrome B-Positive X-Linked

  • Granulomatous Disease, Chronic, X-Linked, Variant
Leukemia, Chronic Myeloid

  • Chronic Myeloid Leukemia

  • Chronic Myelogenous Leukemia

  • CML

  • Chronic Granulocytic Leukemia

  • Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

  • Chronic Myeloid Leukaemia

  • Chronic Granulocytic Leukaemia

  • Chronic Myelogenous Leukaemia

  • Myeloid Leukemia, Chronic

  • Leukemia, Chronic Myelogenous

  • Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

  • Cml - Chronic Myelogenous Leukemia

  • Cgl

  • Chronic Myelocytic Leukemia

  • Leukemia, Chronic Myeloid, Atypical

  • ACML

  • Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

  • Myeloid Leukemia Chronic

  • Leukemia, Myeloid, Chronic

  • Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

  • Cml- [Chronic Myeloid Leukaemia]

  • Cgl - [Chronic Granulocytic Leukaemia]

  • Chronic Myelocytic Leukaemia
Leukemia, Acute Lymphoblastic

  • Acute Lymphoblastic Leukemia

  • ALL

  • Acute Lymphocytic Leukemia

  • Leukemia, Acute Lymphocytic, Susceptibility To, 1

  • Acute Lymphoblastic Leukaemia

  • Precursor Lymphoblastic Lymphoma/Leukemia

  • Precursor Lymphoid Neoplasm

  • Leukemia, Acute Lymphoblastic, Susceptibility To

  • B-Cell Acute Lymphoblastic Leukemia

  • Leukemia, Acute Lymphocytic 1

  • Acute Lymphocytic Leukaemia

  • Acute Lymphoblastic Leukemia/Lymphoma

  • All1

  • Childhood Acute Lymphoblastic Leukemia

  • Leukemia Acute Lymphoblastic 1

  • Leukemia Acute Lymphoblastic B-Hyperdiploid

  • Leukemia Acute Lymphocytic

  • Leukemia Acute Lymphocytic 1

  • Leukemia B-Cell Acute Lymphoblastic

  • Leukemia T-Cell Acute Lymphoblastic

  • Leukemia, Acute Lymphoblastic, 3

  • ALL3

  • Lymphoblastic Leukemia Acute

  • Leukemia, Acute, Lymphoblastic

  • Precursor Cell Lymphoblastic Leukemia Lymphoma

  • Leukemia, Lymphocytic, Acute, L1

  • Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Eye Disease

  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy
Leukemia, Acute Myeloid

  • Acute Myeloid Leukemia

  • Leukemia, Acute Myelogenous

  • Acute Myelogenous Leukemia

  • AML

  • Leukemia, Acute Myeloid, Susceptibility To

  • Acute Myeloblastic Leukemia

  • Leukemia, Acute Myeloid, Reduced Survival In, Somatic

  • Acute Myeloid Leukaemia

  • Leukemia, Myelocytic, Acute

  • Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

  • Secondary Aml

  • Acute Myelocytic Leukemia

  • Acute Myeloid Leukemia, Somatic

  • Leukemia, Acute Myeloid, Somatic

  • Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

  • Acute Myeloblastic Leukaemia

  • Acute Myelogenous Leukaemia

  • Aml - Acute Myeloid Leukemia

  • Acute Myeloid Leukemia With Cebpa Somatic Mutations

  • Aml With Cebpa Somatic Mutations

  • Inherited Acute Myeloid Leukemia

  • Familial Aml

  • Inherited Aml

  • Pure Familial Aml

  • Pure Familial Acute Myeloid Leukemia

  • Secondary Acute Myeloid Leukemia

  • Therapy-Related Aml And Myelodysplastic Syndrome

  • Acute Myeloid Leukemia, Secondary

  • Acute Non-Lymphoblastic Leukemia

  • Acute Non-Lymphocytic Leukemia

  • Acute Biphenotypic Leukemia

  • Acute Undifferentiated Leukemia

  • Acute Myeloblastic Leukaemia With Multilineage Dysplasia

  • Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

  • Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-124129 10074-A4 Inhibitor 98.22% Unkown
HY-184654 MR-39 / Unkown
HY-RS02124 CCND2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17697 Ccnd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24159 Ccnd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CCND2 MGD MGI:88314
Canis familiaris CCND2 VGNC VGNC:38896
Bos taurus CCND2 VGNC VGNC:26963
Rattus norvegicus CCND2 RGD RGD:621083
Others CCND2 NCBI