HTTIPKV
HTTIPKV is a CAF-selective peptide. HTTIPKV specifically binds to recombinant TAS2R9. HTTIPKV selectively localizes to cancer-associated fibroblasts and the stroma of pancreatic ductal adenocarcinoma. Conjugation of HTTIPKV to liposomes enhances tumor accumulation and improves delivery of encapsulated CXCR2 inhibitors, thereby reducing tumor growth. HTTIPKV can be used for research on pancreatic ductal adenocarcinoma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C36H62N10O10
- Molecular Weight:794.94
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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Molecular Weight 794.94
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Formel C36H62N10O10
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SMILES
O=C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CNC=N2)N
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Sequence
His-Thr-Thr-Ile-Pro-Lys-Val
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Sequence Shortening
HTTIPKV
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Keywords
- HTTIPKV
- Biochemical Assay Reagents
- BXPC3/CAF pancreatic ductal adenocarcinoma xenograft
- CXCR2 inhibitor
- GPCR
- TAS2R9
- cancer-associated fibroblast-selective peptide ligand
- cancer-associated fibroblasts
- liposomes
- pancreatic ductal adenocarcinoma
- pancreatic ductal adenocarcinoma stroma
- tumor growth
- Inhibitor
- inhibitor
- inhibit