Mal-PEG12-DOTA
Based on 1 Customer Validation
Mal-PEG12-DOTA is a RDC linker that can be used for the synthesis of RDC.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 95.0%
- Formel: C49H87N7O22
- Molecular Weight:1126.25
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Speicherung:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
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Help & FAQs
Alle Radionuclide-Drug Conjugates (RDCs) Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Beschreibung
In Vitro
Mal-PEG12-DOTA reacts with the targeted molecules (such as antibody fragments, peptides) that have been pre-reduced to free -SH groups at the Mal end to generate Target-Mal-PEG12-DOTA. Then, the DOTA end is incubated with radioactive metal isotopes (such as ⁶⁸GaCl₃) in a weakly acidic or near-neutral buffer. DOTA quantitatively chelates the metal, resulting in the final Target-PEG12-DOTA-⁶⁸Ga reagent.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Appearance Oil
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Molecular Weight 1126.25
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Formel C49H87N7O22
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Color Colorless to light yellow
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SMILES
O=C(O)CN1CCN(CC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 25 mg/mL (22.20 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (243 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.8879 mL | 4.4395 mL | 8.8790 mL | 22.1976 mL |
| 5 mM | 0.1776 mL | 0.8879 mL | 1.7758 mL | 4.4395 mL | |
| 10 mM | 0.0888 mL | 0.4440 mL | 0.8879 mL | 2.2198 mL | |
| 15 mM | 0.0592 mL | 0.2960 mL | 0.5919 mL | 1.4798 mL | |
| 20 mM | 0.0444 mL | 0.2220 mL | 0.4440 mL | 1.1099 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mal-PEG12-DOTA Related Classifications
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