MP-Ala-Ala-PAB
Based on 1 Customer Validation
MP-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.76%
- CAS. Nr.: 1949793-47-8
- Formel: C20H24N4O6
- Molecular Weight:416.43
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1949793-47-8
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Appearance Solid
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Molecular Weight 416.43
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Formel C20H24N4O6
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Color Light yellow to yellow
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SMILES
OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C)NC(CCN2C(C=CC2=O)=O)=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 350 mg/mL (840.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4014 mL | 12.0068 mL | 24.0136 mL | 60.0341 mL |
| 5 mM | 0.4803 mL | 2.4014 mL | 4.8027 mL | 12.0068 mL | |
| 10 mM | 0.2401 mL | 1.2007 mL | 2.4014 mL | 6.0034 mL | |
| 15 mM | 0.1601 mL | 0.8005 mL | 1.6009 mL | 4.0023 mL | |
| 20 mM | 0.1201 mL | 0.6003 mL | 1.2007 mL | 3.0017 mL | |
| 25 mM | 0.0961 mL | 0.4803 mL | 0.9605 mL | 2.4014 mL | |
| 30 mM | 0.0800 mL | 0.4002 mL | 0.8005 mL | 2.0011 mL | |
| 40 mM | 0.0600 mL | 0.3002 mL | 0.6003 mL | 1.5009 mL | |
| 50 mM | 0.0480 mL | 0.2401 mL | 0.4803 mL | 1.2007 mL | |
| 60 mM | 0.0400 mL | 0.2001 mL | 0.4002 mL | 1.0006 mL | |
| 80 mM | 0.0300 mL | 0.1501 mL | 0.3002 mL | 0.7504 mL | |
| 100 mM | 0.0240 mL | 0.1201 mL | 0.2401 mL | 0.6003 mL |
MP-Ala-Ala-PAB Related Classifications
HY-148463 Related Classifications
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