Pradigastat (Standard)
Pradigastat (Standard) is the analytical standard of Pradigastat. This product is intended for research and analytical applications. Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 956136-95-1
- Formel: C25H24F3N3O2
- Molecular Weight:455.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 956136-95-1
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Molecular Weight 455.47
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Formel C25H24F3N3O2
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SMILES
O=C(O)C[C@H]1CC[C@H](C2=CC=C(C3=NC=C(NC4=CC=C(C(F)(F)F)N=C4)C=C3)C=C2)CC1
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Synonyms
LCQ-908 (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Keywords
- Pradigastat (Standard)
- 956136-95-1
- LCQ-908 (Standard)
- Acyltransferase
- BCRP
- OAT
- Reference Standards
- Diacylglycerol acyltransferase
- Diglyceride acyltransferase
- acyl-CoA:cholesterol acyltransferase
- mono- acylglycerol acyltransferase
- Breast cancer resistance protein
- ABCG2
- Organic anion transporter
- DGAT1
- anti-obesity
- anti-diabetic
- OATP
- OAT3
- chylomicrons
- triglyceride
- Inhibitor
- inhibitor
- inhibit