CD238
CD238 is the Kell blood group glycoprotein, a type II transmembrane zinc endopeptidase of the neprilysin (M13) metalloprotease family. It is highly expressed on erythroid precursors and erythrocytes and is also present on endothelial cells and testis. Amino acid substitutions within its large extracellular region define the K and k antigens and more than 30 additional Kell system specificities. Physiologically, Kell protein cleaves big endothelin-3 to release the vasoactive peptide endothelin-3, the best-characterized substrate of the enzyme. Clinically, anti-K antibodies are a frequent cause of hemolytic transfusion reactions and of hemolytic disease of the fetus and newborn, so Kell typing is routine in transfusion medicine.
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CD238 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
