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Rilvegostomig

(Synonyms: AZD-2936)
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Rilvegostomig (AZD-2936) is a bispecific humanized IgG1 antibody targeting PD-1 and TIGIT. Rilvegostomig induces tumor growth inhibition and modulates the tumor immune microenvironment. Rilvegostomig exhibits anti-tumor activity in metastatic non-small cell lung cancer (without prior immune checkpoint inhibitor treatment). Rilvegostomig can be used in research related to metastatic non-small cell lung cancer and endometrial cancer.

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  • Reinheit: 99.00%
  • CAS. Nr.: 2640305-01-5
  • Molecular Weight:146.115 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Rilvegostomig
  • Experimental Validation Results for Rilvegostomig
  • Experimental Validation Results for Rilvegostomig
  • Rilvegostomig Chemical Structure
    Rilvegostomig Chemical Structure
CAS. Nr.: 2640305-01-5
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Rilvegostomig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa-lambda_sulfide

  • 1/16

    Loaded Rilvegostomig on AHC2 biosensor, can bind PD-1 Protein, Human (143a.a, HEK293, His, HY-P7396) with an affinity constant of 7.216E-10 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 FaDu cells with Rilvegostomig (HY-P990704, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Rilvegostomig Chemical Structure
    1/16
  • Rilvegostomig
  • Loaded Rilvegostomig on AHC2 biosensor, can bind PD-1 Protein, Human (143a.a, HEK293, His, HY-P7396) with an affinity constant of 7.216E-10 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 FaDu cells with Rilvegostomig (HY-P990704, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa-lambda_sulfide