SIK2/3-IN-2
SIK2/3-IN-2 (compound 12, compound I-200) is a potent SIK2/3 inhibitor (SIK2 IC50 = 65 nM, SIK3 IC50 = 14 nM). SIK2/3-IN-2 is also a p21-activated protein kinase (PAK) 1 inhibitor with a Ki of 20.7 nM. SIK2/3-IN-2 can be used for hyperproliferative diseases and cancer research, such as Paclitaxel (HY-B0015)-resistant ovarian cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1648864-21-4
- Formel: C25H25ClN6O3
- Molecular Weight:492.96
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
PAK1 20.7 nM (Ki) |
SIK2 65 nM (IC50) |
SIK3 14 nM (IC50) |
Chemical Information
-
CAS. Nr. 1648864-21-4
-
Molecular Weight 492.96
-
Formel C25H25ClN6O3
-
SMILES
O=C(N(C1=N2)C[C@H]3OC[C@@H](CO3)N)C(C4=C(C=C(C5=C(C=CC=N5)C)C=C4)Cl)=CC1=CN=C2NC
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SIK2/3-IN-2 Related Classifications
HY-164534 Related Classifications
Powered by Bioz