TIM-3-IN-1
Based on 1 publication(s) in Google Scholar
TIM-3-IN-1 (Compound 38) is a TIM-3 inhibitor that can be used for the research of cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.90%
- CAS. Nr.: 2883237-04-3
- Formel: C20H16ClN7O3S
- Molecular Weight:469.90
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) TIM-3-IN-1
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2883237-04-3
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Appearance Solid
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Molecular Weight 469.90
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Formel C20H16ClN7O3S
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Color Off-white to light yellow
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SMILES
CC1=NN2C(NC3=CC(Cl)=C(C4=C(C)C=C(NS(C5=NC=CN5)(=O)=O)C=C4)C=C3C2=N1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Signal
Berberine derivative C51 modulates cGAS-STING-TIM-3 axis to reverse immune evasion and inhibit lung cancer growth. [Abstract]2025 Nov 19:139:112258. PMID: 41270814
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (212.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1281 mL | 10.6406 mL | 21.2811 mL | 53.2028 mL |
| 5 mM | 0.4256 mL | 2.1281 mL | 4.2562 mL | 10.6406 mL | |
| 10 mM | 0.2128 mL | 1.0641 mL | 2.1281 mL | 5.3203 mL | |
| 15 mM | 0.1419 mL | 0.7094 mL | 1.4187 mL | 3.5469 mL | |
| 20 mM | 0.1064 mL | 0.5320 mL | 1.0641 mL | 2.6601 mL | |
| 25 mM | 0.0851 mL | 0.4256 mL | 0.8512 mL | 2.1281 mL | |
| 30 mM | 0.0709 mL | 0.3547 mL | 0.7094 mL | 1.7734 mL | |
| 40 mM | 0.0532 mL | 0.2660 mL | 0.5320 mL | 1.3301 mL | |
| 50 mM | 0.0426 mL | 0.2128 mL | 0.4256 mL | 1.0641 mL | |
| 60 mM | 0.0355 mL | 0.1773 mL | 0.3547 mL | 0.8867 mL | |
| 80 mM | 0.0266 mL | 0.1330 mL | 0.2660 mL | 0.6650 mL | |
| 100 mM | 0.0213 mL | 0.1064 mL | 0.2128 mL | 0.5320 mL |