SMCC-PE
SMCC-PE is a dipalmitoylphosphatidylethanolamine derivative modified with the heterobifunctional crosslinker SMCC. SMCC-PE is an intermediate formed by conjugating the SMCC linker with R-phycoerythrin for antibody conjugation.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SMCC-PE (egg PC/chol/SMCC-PE molar ratio 6:3:0.5; 2 h high vacuum drying, 14 min sonication, 20 h incubation at 4°C) forms part of stable, predominantly unilamellar 200 nm liposomes that enable covalent conjugation of SFP-3 peptide with a 10-20% coupling yield, producing a final peptide/total lipid ratio of 1:400[1].
SMCC (10 mg/mL; 1 h) reacts with purified PE at 25°C to form the activated SMCC-PE intermediate, with excess SMCC removed via size-exclusion chromatography[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
[SMCC-PE]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Puyal C, et al. Design of a short membrane-destabilizing peptide covalently bound to liposomes. Biochim Biophys Acta. 1994;1195(2):259-266. [Content Brief]
[2]. Liang M, et al. In vitro evolution of diagnostic antibodies targeting native antigens in plasma by sandwich flow cytometry. Biotechnol J. 2024;19(2):e2300492. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SMCC-PE Related Classifications
HY-D3279 Related Classifications
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