BFF-122
BFF-122 is a compound that selectively inhibits mammalian kynurenine aminotransferase II.
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- CAS No.: 1152314-49-2
- Formule: C17H19FN4O4
- Masse moléculaire:362.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 1, BFF-122
|
Inhibition of human recombinant MBP-KAT1 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hr
Inhibition of human recombinant MBP-KAT1 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hr
|
[PMID: 20684605] |
| HEK293 | IC50 |
0.91 μM
Compound: 1, BFF-122
|
Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hr
Inhibition of human recombinant MBP-KAT2 expressed in HEK293 cells assessed as conversion of L-kynurenine to kynurenic acid after 1 hr
|
[PMID: 20684605] |
Chemical Information
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CAS No. 1152314-49-2
-
Masse moléculaire 362.36
-
Formule C17H19FN4O4
-
SMILES
O=C(O)C(C1=O)=CN2[C@H](COC3=C2C1=CC(F)=C3N4CCN(CC4)N)C
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)