Blapsin B
Blapsin B is a potent 14-3-3 inhibitor and a naturally occurring compound from Blaps japanensis. Blapsin B potently inhibits 14-3-3 protein-protein interactions (PPIs) with an IC50 value of 10.0 μM in the ELISA assay and 2.5 μM in the FP assay, respectively. Blapsin B modulates signaling pathways involved in cell proliferation and transformation. Blapsin B can be used for cancer research.
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- CAS No.: 861145-00-8
- Formule: C15H14O5
- Masse moléculaire:274.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Blapsin B (10 μM) potently inhibits 14-3-3γ protein-protein interactions in an ELISA assay with an IC50 of 10.0 μM[1].
Blapsin B (2.5 μM) potently inhibits 14-3-3 protein-protein interactions in an FP assay with an IC50 of 2.5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 861145-00-8
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Masse moléculaire 274.27
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Formule C15H14O5
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SMILES
OC1=CC=C(C2OCCC3=CC(O)=C(C=C32)O)C=C1O
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Structure Classification
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Initial Source
from the insect Blaps japanensis
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Blapsin B Related Classifications
HY-N19296 Related Classifications
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