Clathrin-IN-2
Based on 1 Customer Validation
Clathrin-IN-2 is potent inhibitor of clathrin mediated endocytosis (CME) with an IC50 value of 2.3 μM. Clathrin-IN-2 also has inhibitiory for dyn I GTPase with an IC50 value of 7.7 μM.
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- Pureté : 98.77%
- CAS No.: 2650733-69-8
- Formule: C17H18Br2N2O
- Masse moléculaire:426.15
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Stockage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Clathrin-IN-2 (Compound 8a) can inhibit clathrin mediated endocytosis with an IC50 value of 2.3 μM[1].
Clathrin-IN-2 has inhibitiory for dyn I GTPase with an IC50 value of 7.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2650733-69-8
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Appearance Solid
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Masse moléculaire 426.15
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Formule C17H18Br2N2O
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Color White to off-white
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SMILES
CN(C[C@@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
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Fiche technique (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clathrin-IN-2 Related Classifications
HY-152217 Related Classifications
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