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Cat. No.: HY-107082

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Dioxolane T

Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity.

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CAS No.: 136982-89-3
Formule: C₉H₁₂N₂O₅
Masse moléculaire:228.20

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Dioxolane T Chemical Structure

CAS No.: 136982-89-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity^[1].

Voir tous les produits spécifiques à Isoform HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	EC₅₀	0.68 μM Compound: DOT	Antiviral activity against HIV1 LAI infected in CEM cells Antiviral activity against HIV1 LAI infected in CEM cells	[PMID: 19153047]
CCRF-CEM	IC₅₀	>100 μM Compound: DOT	Cytotoxicity against human CEM cells after 3 days by MTT assay Cytotoxicity against human CEM cells after 3 days by MTT assay	[PMID: 19153047]
PBMC	IC₅₀	>100 μM Compound: DOT	Cytotoxicity against human PBM cells after 3 days by MTT assay Cytotoxicity against human PBM cells after 3 days by MTT assay	[PMID: 19153047]
Vero	IC₅₀	>100 μM Compound: 11	Cytotoxicity in vero cells. Cytotoxicity in vero cells.	[PMID: 1597854]
Vero	IC₅₀	>100 μM Compound: DOT	Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay	[PMID: 19153047]

Chemical Information

CAS No. 136982-89-3
Masse moléculaire 228.20
Formule C₉H₁₂N₂O₅
SMILES

O=C1N(C=C(C(N1)=O)C)[C@@H]2O[C@@H](OC2)CO
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kim HO, et al. Asymmetric synthesis of 1, 3-dioxolane-pyrimidine nucleosides and their anti-HIV activity. Journal of Medicinal Chemistry. 1992 May;35(11):1987-95. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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Dioxolane T

Voir tous les produits spécifiques à Isoform HIV