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Cat. No.: HY-128037

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FTase-IN-2

FTase-IN-2 (Compound 2) is a farnesyltransferase inhibitor, with IC₅₀ values of 150 nM and 1500 nM against FTase and GGTase I, respectively. FTase-IN-2 is not farnesylated by FTase, thus avoiding metabolic inactivation.

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CAS No.: 156707-43-6
Formule: C₁₅H₂₁N₃O₄S₂
Masse moléculaire:371.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

FTase-IN-2 Chemical Structure

CAS No.: 156707-43-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 156707-43-6
Masse moléculaire 371.47
Formule C₁₅H₂₁N₃O₄S₂
SMILES

N(C([C@H](CS)N)=O)C1=CC=C(C(N[C@@H](CCSC)C(O)=O)=O)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Vogt A, et al. A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing. The Journal of biological chemistry. 1995 Jan 13;270(2):660-4. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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