ICI 185282
ICI 185282 is a potent, selective, orally active thromboxane A2 (TXA₂) receptor antagonist. ICI 185282 causes dose-dependent inhibition of U-46619 (HY-108566)-induced platelet aggregation ex-vivo in guinea-pig. ICI 185,282 inhibits bronchospasm induced by U-46619, PGD2 (HY-101988), PGF2α (HY-12956), arachidonic acid (HY-109590), LTD4 and PAF (HY-108635) in vivo. ICI 185282 can be used for bronchial asthma research.
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- CAS No.: 106393-80-0
- Formule: C18H21F3O5
- Masse moléculaire:374.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
TXA2 Receptor |
Chemical Information
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CAS No. 106393-80-0
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Masse moléculaire 374.35
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Formule C18H21F3O5
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SMILES
O=C(O)CCC/C=C\C[C@@H]1[C@H](C2=CC=CC=C2O)O[C@H](C(F)(F)F)OC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ICI 185282 Related Classifications
HY-101235 Related Classifications
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