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United States

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Cat. No.: HY-123608

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JE-2178

JE-2178 is an orally available HIV-1 protease inhibitor with IC₅₀ and K_i values are 15 and 0.318 nM respectively. JE-2178 has antiviral activity.

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CAS No.: 210181-19-4
Formule: C₃₅H₅₁N₅O₆S
Masse moléculaire:669.87

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

JE-2178 Chemical Structure

CAS No.: 210181-19-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

JE-2178 is an orally available HIV-1 protease inhibitor with IC₅₀ and K_i values are 15 and 0.318 nM respectively. JE-2178 has antiviral activity^[1].

Chemical Information

CAS No. 210181-19-4
Masse moléculaire 669.87
Formule C₃₅H₅₁N₅O₆S
SMILES

O[C@@H]([C@H](CC1=CC=CC=C1)NC([C@H](C(C)C)NC(COC2=CC=CC(N(C)C)=C2)=O)=O)C(N3CSC(C)([C@H]3C(NC(C)(C)C)=O)C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mimoto T, et al. Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere. Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1310-26. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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