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Cat. No.: HY-N14722

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Lactonamycin

Lactonamycin had strong activity against Gram-positive bacteria including Staphylococcus, Streptococcus, Enterococcus, MRSA (MIC of 0.39-0.78 μg/mL) and VRE (MIC of 0.39-0.78 μg/mL). Lactonamycin also has inhibitory effect on L-1210, P388, S180, FS-3, Ehrlich, B16-BL5 and other tumor cell lines (IC₅₀s of 0.06-3.3 μg/mL).

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CAS No.: 182234-02-2
Formule: C₂₈H₂₇NO₁₂
Masse moléculaire:569.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Lactonamycin Chemical Structure

CAS No.: 182234-02-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
EL4	IC₅₀	112 nM Compound: 34	Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 38092421]
L1210	IC₅₀	153 nM Compound: 34	Antiproliferative activity against mouse L1210 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against mouse L1210 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38092421]

Chemical Information

CAS No. 182234-02-2
Masse moléculaire 569.51
Formule C₂₈H₂₇NO₁₂
SMILES

CO[C@](OC1)(CC(O2)=O)[C@]2(C(C(C(C3=O)=CC4=C5)=C(O)C4=C6C(C(N(C6)C)=O)=C5O)=O)[C@@]13O[C@@H]7O[C@H]([C@H](CC7)O)C
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Philip J Parsons, et al. An Approach to the Core of Lactonamycin. Org Lett. 2017 May 19;19(10):2533-2535. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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