Nefazodone (Standard)
Nefazodone (Standard) is the analytical standard of Nefazodone. This product is intended for research and analytical applications. Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT2A receptors, and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction.
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- Pureté : 98%
- CAS No.: 83366-66-9
- Formule: C25H32ClN5O2
- Masse moléculaire:470.01
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-119209
NefazodonePhenylpiperazine Antidepressant -
HY-B0478A
TrazodoneSerotonin Receptor Antagonist -
HY-15419A
RS-1274455-HT2B Antagonist -
HY-B0731A
PerospironeAntipsychotic Agent -
HY-17390A
Loxapine succinateDopamine/5-HT Receptor Inhibitor -
HY-17390AR
Loxapine succinate (Standard)Dopamine/5-HT Receptor Inhibitor -
HY-107434
MolindoneDopamine D2/D5 Receptor Antagonist -
HY-B0478AR
Trazodone (Standard)Serotonin Receptor Antagonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 83366-66-9
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Masse moléculaire 470.01
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Formule C25H32ClN5O2
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SMILES
O=C1N(N=C(N1CCOC2=CC=CC=C2)CC)CCCN3CCN(CC3)C4=CC=CC(Cl)=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Davis R, et al. A review of its pharmacology and clinical efficacy in the management of major depression. Drugs. 1997 Apr;53(4):608-36. [Content Brief]
[2]. Dykens JA, et al. In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone. Toxicol Sci. 2008 Jun;103(2):335-45. [Content Brief]
[3]. Freire-Garabal M, et al. Effects of nefazodone on the immune system of mice. Eur Neuropsychopharmacol. 2000 Jul;10(4):255-64. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nefazodone (Standard) Related Classifications
HY-119209R Related Classifications
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