Somantadine
Based on 1 Customer Validation
Somantadine, an adamantane derivative, is an antiviral agent with high cross-reactivity with anti-amantadine monoclonal antibodies. Somantadine can be used for research of coronavirus-related diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98.58%
- CAS No.: 79594-24-4
- Formule: C14H25N
- Masse moléculaire:207.36
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Stockage:
-80°C
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Somantadine (2 h coating; 1 h blocking; 30 min competitive incubation) is recognized with extremely high cross-reactivity by anti-amantadine monoclonal antibodies 3F2, 1A12, 7E2, and 7G2, with IC50 values ranging from 0.08 to 0.25 ng/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 79594-24-4
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Appearance Solid
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Masse moléculaire 207.36
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Formule C14H25N
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Color White to off-white
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SMILES
CC(C)(CC12CC3CC(CC(C3)C1)C2)N
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Livraison
Shipping with dry ice.
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Stockage
-80°C
Solvant et solubilité
In Vitro:
DMSO : 11 mg/mL (53.05 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
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Fiche technique (273 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.8225 mL | 24.1127 mL | 48.2253 mL | 120.5633 mL |
| 5 mM | 0.9645 mL | 4.8225 mL | 9.6451 mL | 24.1127 mL | |
| 10 mM | 0.4823 mL | 2.4113 mL | 4.8225 mL | 12.0563 mL | |
| 15 mM | 0.3215 mL | 1.6075 mL | 3.2150 mL | 8.0376 mL | |
| 20 mM | 0.2411 mL | 1.2056 mL | 2.4113 mL | 6.0282 mL | |
| 25 mM | 0.1929 mL | 0.9645 mL | 1.9290 mL | 4.8225 mL | |
| 30 mM | 0.1608 mL | 0.8038 mL | 1.6075 mL | 4.0188 mL | |
| 40 mM | 0.1206 mL | 0.6028 mL | 1.2056 mL | 3.0141 mL | |
| 50 mM | 0.0965 mL | 0.4823 mL | 0.9645 mL | 2.4113 mL |
Somantadine Related Classifications
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