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Cat. No.: HY-187906

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Sovutrecdeg

Sovutrecdeg is a tropomyosin receptor kinase (TRK) degrader with antitumor activity. Sovutrecdeg can be used in tumor-related research.

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CAS No.: 2412058-69-4
Formule: C₄₇H₄₇F₂N₉O₆
Masse moléculaire:871.93

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Please store the product under the recommended conditions in the Certificate of Analysis.

Sovutrecdeg Chemical Structure

CAS No.: 2412058-69-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Sovutrecdeg is a tropomyosin receptor kinase (TRK) degrader with antitumor activity. Sovutrecdeg can be used in tumor-related research^[1].

Voir tous les produits spécifiques à Isoform Trk Receptor :

Chemical Information

CAS No. 2412058-69-4
Masse moléculaire 871.93
Formule C₄₇H₄₇F₂N₉O₆
SMILES

O=C(C1=CC=C(N2CCN(CC3CN(C3)C4=CC=C5C(N(C6C(NC(CC6)=O)=O)C(C5=C4)=O)=O)CC2)C=C1NC7CCOCC7)NC8=NNC9=C8C=C(CC%10=CC(F)=CC(F)=C%10)C=C9
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Animals and Diseases

Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. World Health Organization. International Nonproprietary Names for Pharmaceutical Substances (INN) — Proposed INN: List 135. WHO Drug Information. 2026; 40(2).

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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