Chrysoobtusin 2-β-D-glucoside
Chrysoobtusin 2-β-D-glucoside is an anthraquinone glycoside found in Cassia obtusifolia. Chrysoobtusin 2-β-D-glucoside may have potential anti-inflammatory and antioxidant activities.
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- CAS No.: 96820-54-1
- 화학식: C25H28O12
- 분자량:520.48
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Chemical Information
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CAS No. 96820-54-1
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분자량 520.48
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화학식 C25H28O12
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SMILES
COC1=C2C(C(C3=CC(C)=C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C(OC)=C3C2=O)=O)=CC(OC)=C1OC
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Research Protocol for Inflammation-related Diseases
The NLRP3 inflammasome is a cytosolic innate immune signaling platform that integrates priming signals and danger-signal activation to promote caspase-1 activation, maturation of IL-1β and IL-18, and gasdermin D-mediated pyroptotic cell death. The core experimental logic is to determine whether inflammatory disease phenotypes are driven by increased NLRP3 expression, ASC-containing inflammasome assembly, caspase-1 cleavage, GSDMD cleavage, and extracellular release of IL-1β/IL-18 rather than by nonspecific cell injury alone. The pathway is strongly linked to inflammation-related disease phenotypes because monosodium urate crystals activate NALP3/NLRP3 inflammasome signaling in gout-like crystal inflammation, cholesterol crystals activate NLRP3 inflammasomes in atherogenesis models, and DSS-induced intestinal inflammation has been reported to involve NLRP3 inflammasome activity. However, experimental colitis studies also show context-dependent protective effects of NLRP3 inflammasome co
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)