Clobetasone 17-Propionate
Based on 1 Customer Validation
Clobetasone propionate is a corticosteroid. Formulations containing clobetasol propionate have been used in the treatment of eczema, psoriasis, and lupus.
For research use only. We do not sell to patients.
- CAS No.: 25122-56-9
- Formula: C25H30ClFO5
- Molecular Weight:464.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
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Halofuginone hydrochlorideNatural Product -
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Mometasone (Standard)Inhaled Glucocorticoid
Biological Activity
Description
Chemical Information
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CAS No. 25122-56-9
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Molecular Weight 464.95
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Formula C25H30ClFO5
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SMILES
O=C(CCl)[C@]([C@@H](C)C1)(OC(CC)=O)[C@](C2)(C)[C@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)C2=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Imiquimod-Induced Psoriasiform Dermatitis
Imiquimod (IMQ)-induced psoriasiform dermatitis is a widely used murine model in which topical application of IMQ, a Toll-like receptor 7 (TLR7) agonist, triggers innate immune activation in the skin and induces a psoriasis-like inflammatory cascade characterized by epidermal hyperplasia, immune cell infiltration, and cytokine production dominated by the IL-23/IL-17 axis. This inflammatory response is mediated through activation of dendritic cells and downstream induction of IL-23, IL-17A, IL-22, and related pro-inflammatory mediators, recapitulating key features of human plaque psoriasis and enabling mechanistic and therapeutic studies. The model is commonly induced using Aldara (5% IMQ cream) applied topically to murine skin, resulting in rapid onset of erythema, scaling, and thickening that can be quantified as disease severity indices and validated histologically.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clobetasone 17-Propionate Related Classifications
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