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Cat. No.: HY-P1287

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Conantokin-T

Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC₅₀ value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 127476-26-0
화학식: C₁₁₀H₁₇₅N₃₁O₄₅S
분자량:2683.81

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Conantokin-T Chemical Structure

CAS No.: 127476-26-0

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

IC₅₀ & Target

IC50: 2 μM (NMDA)^[1]

All iGluR Isoforms :

In Vitro

Conantokin-T produces a partial antagonism of NMDA receptor function with an IC₅₀ value of 2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Conantokin-T induces sleep-like symptoms in young mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 127476-26-0
분자량 2683.81
화학식 C₁₁₀H₁₇₅N₃₁O₄₅S
Sequence Shortening

GE-{Gla}-{Gla}-YQKML-{Gla}-NLR-{Gla}-AEVKKNA-NH2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J A Haack, et al. Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity. J Biol Chem. 1990 Apr 15;265(11):6025-9. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References

상품명:
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수량:
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상품명:
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Conantokin-T

Spermidine hydrochloride

5,7-Dichlorokynurenic acid

TCN 201

(RS)-CPP

Spermidine hydrochloride (Standard)

(-)-Dizocilpine maleate

(R)-CPP

DQP-1105

1-Aminocyclobutanecarboxylic acid

Selfotel

Arcaine sulfate

L-689560

All iGluR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

Conantokin-T

Spermidine hydrochloride

5,7-Dichlorokynurenic acid

TCN 201

(RS)-CPP

Spermidine hydrochloride (Standard)

(-)-Dizocilpine maleate

(R)-CPP

DQP-1105

1-Aminocyclobutanecarboxylic acid

Selfotel

Arcaine sulfate

L-689560

All iGluR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Conantokin-T Related Classifications

HY-P1287 Related Classifications

Bioz