Curvulol
Curvulol is an antimicrobial agent with a polyketide structure. Curvulol can be isolated from Taxus baccata ( Chaetosphaeronema achilleae). Curvulol has a significant cytotoxicity against L929 and KB-3-1 cells, and strongly inhibits Staphylococcus aureus biofilm formation with a MIC of 64 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 15817-76-2
- Formula: C10H12O4
- Molecular Weight:196.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Curvulol (Compound 7) shows an antimicrobial activity against Rhodoturula glutinis DSM 10134, Schizosaccharomyces pombe DSM 70572, Staphylococcus aureus DSM 346 and Bacillus subtilis DSM 10 with a MIC of 33.33 μg/mL[1].
Curvulol has a significant cytotoxicity with IC50 s of 5.5 and 7.5 μg/mL for L929 and KB-3-1 cells, respectively[1].
Curvulol (4-256 μg/mL) strongly inhibits Staphylococcus aureus biofilm formation of 96.18% at 256 μg/mL, and with a MIC of 64 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15817-76-2
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Molecular Weight 196.20
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Formula C10H12O4
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SMILES
OC1=C2C(CO[C@H]2C)=CC(OC)=C1O
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Structure Classification
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Initial Source
Chaetosphaeronema achilleae
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Curvulol Related Classifications
HY-N15595 Related Classifications
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