D-myo-Inositol-1,2,4,5,6-pentaphosphate sodium salt  (Synonyms: Ins(1,2,4,5,6)P5 sodium salt; 1,2,4,5,6-IP5 sodium salt)

D-myo-Inositol-1,2,4,5,6-pentaphosphate (Ins(1,2,4,5,6)P5) sodium salt is one of several different inositol oligophosphate isomers involved in signal transduction. In human Jurkat T lymphocytes, Ins(1,2,4,5,6)P5 (sodium salt) is phosphorylated to InsP6 by 1/3 kinase. D-myo-Inositol-1,2,4,5,6-pentaphosphate sodium salt is involved in calcium signaling^[1].

689.96

C₆H₁₂Na₅O₂₁P₅

Liquid

Colorless to light yellow

O[C@@H]1[C@H](OP(O)(O[Na])=O)[C@H](OP(O)(O[Na])=O)[C@@H](OP(O)(O[Na])=O)[C@H](OP(O)(O[Na])=O)[C@H]1OP(O)(O[Na])=O

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Guse AH, et al. T-cell receptor-mediated metabolism of inositol polyphosphates in Jurkat T-lymphocytes. Identification of a D-myo-inositol 1,2,3,4,6-pentakisphosphate-2-phosphomonoesterase activity, a D-myo-inositol 1,3,4,5,6-pentakisphosphate-1/3-phosphatase activity and a D/L-myo-inositol 1,2,4,5,6-pentakisphosphate-1/3-kinase activity. J Biol Chem. 1991 Dec 25;266(36):24498-502.  [Content Brief]