Dacomitinib impurity 12
Based on 1 Customer Validation
Dacomitinib impurity 12 is an impurity of Dacomitinib (HY-13272).
For research use only. We do not sell to patients.
- CAS No.: 2803451-99-0
- Formula: C15H12Cl2N4O
- Molecular Weight:335.19
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
Chemical Information
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CAS No. 2803451-99-0
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Appearance Solid
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Molecular Weight 335.19
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Formula C15H12Cl2N4O
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Color Light yellow to green yellow
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SMILES
NC1=CC2=C(NC3=CC=C(Cl)C(Cl)=C3)N=CN=C2C=C1OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (74.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9834 mL | 14.9169 mL | 29.8338 mL | 74.5846 mL |
| 5 mM | 0.5967 mL | 2.9834 mL | 5.9668 mL | 14.9169 mL | |
| 10 mM | 0.2983 mL | 1.4917 mL | 2.9834 mL | 7.4585 mL | |
| 15 mM | 0.1989 mL | 0.9945 mL | 1.9889 mL | 4.9723 mL | |
| 20 mM | 0.1492 mL | 0.7458 mL | 1.4917 mL | 3.7292 mL | |
| 25 mM | 0.1193 mL | 0.5967 mL | 1.1934 mL | 2.9834 mL | |
| 30 mM | 0.0994 mL | 0.4972 mL | 0.9945 mL | 2.4862 mL | |
| 40 mM | 0.0746 mL | 0.3729 mL | 0.7458 mL | 1.8646 mL | |
| 50 mM | 0.0597 mL | 0.2983 mL | 0.5967 mL | 1.4917 mL | |
| 60 mM | 0.0497 mL | 0.2486 mL | 0.4972 mL | 1.2431 mL |