SDH-IN-14
Based on 1 Customer Validation
SDH-IN-14 (Compound Z2) is an inhibitor of succinate dehydrogenase (SDH). SDH-IN-14 has antifungal activity (EC50=2.7 μg/mL) against B.cinerea. SDH-IN-14 acts by disrupting the integrity of the cell wall and cell membrane.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.44%
- Formel: C21H20N4O2S2
- Molecular Weight:424.54
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
SDH-IN-14 (0-100 μg/mL; 12 h) in B.cinerea reveals that cell membrane permeability increased with increasing concentration[1].
SDH-IN-14 (0-200 μg/mL; 10 h) in B.cinerea shows an increase in MDA content with increasing concentration and oxidative damage to the cell membrane[1].
SDH-IN-14 (12.5-100 μg/mL; 24 h) in B.cinerea shows a concentration-dependent inhibition of SDH activity[1].
SDH-IN-14 shows antifungal activity of inhibition rat=96.7% (B.cinerea); 52.6% (R.solani); 69.9% (P.capsici); 59.2% (=S.sclerotiorum); 34.5% (=F.graminearum); 70.6% (Tomato Botrytis cinerea); 15.0% (=F.asiaticum), respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 424.54
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Formel C21H20N4O2S2
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Color White to off-white
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SMILES
O=C(NC1=NN=C(SCC(O)CN2C=CC3=C2C=CC=C3)S1)C4=CC=CC=C4C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (235.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3555 mL | 11.7775 mL | 23.5549 mL | 58.8873 mL |
| 5 mM | 0.4711 mL | 2.3555 mL | 4.7110 mL | 11.7775 mL | |
| 10 mM | 0.2355 mL | 1.1777 mL | 2.3555 mL | 5.8887 mL | |
| 15 mM | 0.1570 mL | 0.7852 mL | 1.5703 mL | 3.9258 mL | |
| 20 mM | 0.1178 mL | 0.5889 mL | 1.1777 mL | 2.9444 mL | |
| 25 mM | 0.0942 mL | 0.4711 mL | 0.9422 mL | 2.3555 mL | |
| 30 mM | 0.0785 mL | 0.3926 mL | 0.7852 mL | 1.9629 mL | |
| 40 mM | 0.0589 mL | 0.2944 mL | 0.5889 mL | 1.4722 mL | |
| 50 mM | 0.0471 mL | 0.2355 mL | 0.4711 mL | 1.1777 mL | |
| 60 mM | 0.0393 mL | 0.1963 mL | 0.3926 mL | 0.9815 mL | |
| 80 mM | 0.0294 mL | 0.1472 mL | 0.2944 mL | 0.7361 mL | |
| 100 mM | 0.0236 mL | 0.1178 mL | 0.2355 mL | 0.5889 mL |
SDH-IN-14 Related Classifications
HY-161504 Related Classifications
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