(E)-2-Nitrocinnamic acid
Based on 1 Customer Validation
(E)-2-Nitrocinnamic acid (Compound 1k) is an Acetylcholinesterase inhibitor. (E)-2-Nitrocinnamic acid is applicable to research related to Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 1013-96-3
- Formula: C9H7NO4
- Molecular Weight:193.16
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE |
In Vitro
(E)-2-Nitrocinnamic acid (10 μM) exhibits weak inhibition of AChE (8.52% inhibition at 10 μM) and negligible inhibition of BChE (2.11% inhibition at 10 μM), with a calculated AChE binding energy of -6.33 kcal/mol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1013-96-3
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Appearance Solid
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Molecular Weight 193.16
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Formula C9H7NO4
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SMILES
OC(/C=C/C1=C(C=CC=C1)[N+]([O-])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(E)-2-Nitrocinnamic acid Related Classifications
HY-W053641 Related Classifications
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