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Cat. No.: HY-N8870

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Physapruin A

Physapruin A is a withanolide that can be found in Physalis pruinosa.

For research use only. We do not sell to patients.

CAS No.: 155178-03-3
Formula: C₂₈H₃₈O₇
Molecular Weight:486.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Physapruin A Chemical Structure

CAS No.: 155178-03-3

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Physapruin A is a withanolide that can be found in Physalis pruinosa^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
ACHN	IC₅₀	1 μM Compound: 20	Cytotoxicity against human ACHN cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Cytotoxicity against human ACHN cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay	[PMID: 28617598]
CWR22R	IC₅₀	0.07 μM Compound: 20	Cytotoxicity against human 22Rv1 cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Cytotoxicity against human 22Rv1 cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay	[PMID: 28617598]
HFF	IC₅₀	>2 μM Compound: 20	Cytotoxicity against HFF cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Cytotoxicity against HFF cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay	[PMID: 28617598]
LNCaP	IC₅₀	0.11 μM Compound: 20	Cytotoxicity against human LNCAP cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Cytotoxicity against human LNCAP cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay	[PMID: 28617598]
M14	IC₅₀	>2 μM Compound: 20	Cytotoxicity against human M14 cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Cytotoxicity against human M14 cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay	[PMID: 28617598]
SK-MEL-28	IC₅₀	>2 μM Compound: 20	Cytotoxicity against human SK-MEL-28 cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay Cytotoxicity against human SK-MEL-28 cells assessed as reduction in cell viability after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay	[PMID: 28617598]

Chemical Information

CAS No. 155178-03-3
Molecular Weight 486.60
Formula C₂₈H₃₈O₇
SMILES

O[C@@]([C@@](CC=C([C@H]1O)[C@@]2(C(C=C1)=O)C)([H])[C@]2([H])CC3)(CC[C@](O)4[C@@](O)([C@@](OC5=O)([H])CC(C)=C5C)C)[C@]34C
Structure Classification
- Steroids
Initial Source
- Plants
- Solanaceae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kazushi SHINGU, et al. Physapruins A and B, Two New Withanolides from Physalis pruinosa BAILEY. Chemical and Pharmaceutical Bulletin, 1993, 41 (10): 1873-1875.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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