Dechloro Rivaroxaban

Cat. No.: HY-76971 Purity: 99.94%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Dechloro Rivaroxaban is a highly selective, orally active inhibitor of Factor Xa. Dechloro Rivaroxaban inhibits human free FXa with a K_i of 0.4 nM. Dechloro Rivaroxaban inhibits prothrombinase activity and fibrin-associated FXa activity with IC₅₀s of 2.1 nM and 92 nM, respectively.

For research use only. We do not sell to patients.

Dechloro Rivaroxaban Chemical Structure

CAS No. : 1415566-28-7

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 253	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 253	In-stock	Estimated Time of Arrival: December 31
Solid
25 mg	USD 230	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 580	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 1100	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

401.44

Formula

C₁₉H₁₉N₃O₅S

CAS No.

1415566-28-7

Appearance

Solid

Color

White to off-white

SMILES

O=C1N(C2=CC=C(N3C(COCC3)=O)C=C2)C[C@@H](O1)CNC(C4=CC=CS4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (124.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4910 mL	12.4552 mL	24.9103 mL
5 mM	0.4982 mL	2.4910 mL	4.9821 mL
10 mM	0.2491 mL	1.2455 mL	2.4910 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.94%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (248 KB) RP-HPLC (191 KB)

Handling Instructions (2659 KB)

References

[1]. Lang D, et al. In vitro metabolism of rivaroxaban, an oral, direct factor Xa inhibitor, in liver microsomes and hepatocytes of rats, dogs, and humans. Drug Metab Dispos. 2009 May;37(5):1046-55. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.4910 mL	12.4552 mL	24.9103 mL	62.2758 mL
	5 mM	0.4982 mL	2.4910 mL	4.9821 mL	12.4552 mL
	10 mM	0.2491 mL	1.2455 mL	2.4910 mL	6.2276 mL
	15 mM	0.1661 mL	0.8303 mL	1.6607 mL	4.1517 mL
	20 mM	0.1246 mL	0.6228 mL	1.2455 mL	3.1138 mL
	25 mM	0.0996 mL	0.4982 mL	0.9964 mL	2.4910 mL
	30 mM	0.0830 mL	0.4152 mL	0.8303 mL	2.0759 mL
	40 mM	0.0623 mL	0.3114 mL	0.6228 mL	1.5569 mL
	50 mM	0.0498 mL	0.2491 mL	0.4982 mL	1.2455 mL
	60 mM	0.0415 mL	0.2076 mL	0.4152 mL	1.0379 mL
	80 mM	0.0311 mL	0.1557 mL	0.3114 mL	0.7784 mL
	100 mM	0.0249 mL	0.1246 mL	0.2491 mL	0.6228 mL