DGKα-IN-7
DGKα-IN-7 is a DGKα inhibitor with the IC50 of 6.225 nM, extracted from patent WO2022271684 (compound 100). DGKα-IN-7 has the potential for cancer study.
For research use only. We do not sell to patients.
- CAS No.: 2886092-50-6
- Formula: C23H17F5N6
- Molecular Weight:472.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
6.225 nM (DGKα)
Chemical Information
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CAS No. 2886092-50-6
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Molecular Weight 472.41
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Formula C23H17F5N6
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SMILES
FC1=C(F)C(C(N2C3=C(CCC2)C(C#CC(C)(C(F)(F)F)C)=CN=C3)=NC4=NN=CN45)=C5C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)