DHODH-IN-30
DHODH-IN-30 (compound 4g) is a potent human dihydroorotate dehydrogenase (hDHODH) inhibitor with an IC50 of 32 nM. DHODH-IN-30 exhibits protective effects against oxidative stress.
For research use only. We do not sell to patients.
- Formula: C21H16N2O5
- Molecular Weight:376.36
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
Molecular Weight 376.36
-
Formula C21H16N2O5
-
SMILES
O=C(O)[C@H](CC1=CC=C(O)C=C1)N(C2=O)C(C3=C2C4=CC=CC=C4N=C3C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dimitrijević MG, et al. First bioconjugates in the role of highly effective human dihydroorotate dehydrogenase inhibitors: Synthesis, pharmacological, toxicological and hydrolytic stability studies of α-amino acid-modified pyrrolo[3,4-c]quinoline-1,3-dione scaffold. Eur J Med Chem. 2025 Nov 5;297:117972. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)