Diethylene glycol bis(p-toluenesulfonate)
Based on 1 Customer Validation
Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.83%
- CAS No.: 7460-82-4
- Formula: C18H22O7S2
- Molecular Weight:414.49
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-W004816
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Triethylene glycol bis(p-toluenesulfonate) -
HY-W004447
Pentaethylene glycol di(p-toluenesulfonate) -
HY-W011077R
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HY-140367
Bis-Tos-PEG6PROTAC Linkers -
HY-141230
Hexaethylene glycolPROTAC Linkers -
HY-140368
Bis-Tos-PEG7PROTAC Linkers -
HY-130985
9-Decyn-1-olPROTAC Linker -
HY-140369
Tos-PEG8-TosPROTAC Linkers -
HY-140370
Tos-PEG9-TosPROTAC Linkers -
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Ms-PEG2-MSPROTAC Linkers -
HY-140371
Tos-PEG12-Tos
All PROTAC Linkers Isoforms
More
Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 7460-82-4
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Appearance Solid
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Molecular Weight 414.49
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Formula C18H22O7S2
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Color White to off-white
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SMILES
O=S(C1=CC=C(C)C=C1)(OCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O
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Synonyms
Diethylene glycol di(p-toluenesulfonate); Bis-Tos-PEG2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (241.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4126 mL | 12.0630 mL | 24.1260 mL | 60.3151 mL |
| 5 mM | 0.4825 mL | 2.4126 mL | 4.8252 mL | 12.0630 mL | |
| 10 mM | 0.2413 mL | 1.2063 mL | 2.4126 mL | 6.0315 mL | |
| 15 mM | 0.1608 mL | 0.8042 mL | 1.6084 mL | 4.0210 mL | |
| 20 mM | 0.1206 mL | 0.6032 mL | 1.2063 mL | 3.0158 mL | |
| 25 mM | 0.0965 mL | 0.4825 mL | 0.9650 mL | 2.4126 mL | |
| 30 mM | 0.0804 mL | 0.4021 mL | 0.8042 mL | 2.0105 mL | |
| 40 mM | 0.0603 mL | 0.3016 mL | 0.6032 mL | 1.5079 mL | |
| 50 mM | 0.0483 mL | 0.2413 mL | 0.4825 mL | 1.2063 mL | |
| 60 mM | 0.0402 mL | 0.2011 mL | 0.4021 mL | 1.0053 mL | |
| 80 mM | 0.0302 mL | 0.1508 mL | 0.3016 mL | 0.7539 mL | |
| 100 mM | 0.0241 mL | 0.1206 mL | 0.2413 mL | 0.6032 mL |
Diethylene glycol bis(p-toluenesulfonate) Related Classifications
HY-W010948 Related Classifications
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