1. Alkaloids
  2. Dihydrolycorine

Dihydrolycorine 

Cat. No.: HY-N2403 Purity: 98.44%
Handling Instructions

Dihydrolycorine, isolated from Lycoris radiate Herb, is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step.

For research use only. We do not sell to patients.

Dihydrolycorine Chemical Structure

Dihydrolycorine Chemical Structure

CAS No. : 6271-21-2

Size Price Stock Quantity
5 mg USD 99 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
20 mg USD 286 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Dihydrolycorine, isolated from Lycoris radiate Herb, is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step[1][2].

IC50 & Target

Protein synthesis[1]

In Vivo

Dihydrolycorine inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA2 values of 5.93 and 6.35, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

289.33

Formula

C₁₆H₁₉NO₄

CAS No.

6271-21-2

SMILES

O[[email protected]]1[[email protected]]2([H])[[email protected]]3([H])N(CC[[email protected]]3([H])C[[email protected]@H]1O)CC4=CC(OCO5)=C5C=C24

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (43.20 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4563 mL 17.2813 mL 34.5626 mL
5 mM 0.6913 mL 3.4563 mL 6.9125 mL
10 mM 0.3456 mL 1.7281 mL 3.4563 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1.25 mg/mL (4.32 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.25 mg/mL (4.32 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

DihydrolycorineOthersInhibitorinhibitorinhibit

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Product Name:
Dihydrolycorine
Cat. No.:
HY-N2403
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