1. Alkaloid
  2. Dihydrolycorine

Dihydrolycorine 

Cat. No.: HY-N2403
Handling Instructions

Dihydrolycorine is isolated from Lycoris radiate Herb with antihypertensive and neuroprotective activities. Dihydrolycorine is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step.

For research use only. We do not sell to patients.

Dihydrolycorine Chemical Structure

Dihydrolycorine Chemical Structure

CAS No. : 6271-21-2

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Description

Dihydrolycorine is isolated from Lycoris radiate Herb with antihypertensive and neuroprotective activities[1]. Dihydrolycorine is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step[2].

IC50 & Target

Protein synthesis[2]

In Vivo

Dihydrolycorine reduces infarct size, cerebral edema, and myeloperoxidase activity in a rat model of focal cerebral ischemia-reperfusion injury when administered following reperfusion[1].
Dihydrolycorine inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA2 values of 5.93 and 6.35, respectively[3].

Molecular Weight

289.33

Formula

C₁₆H₁₉NO₄

CAS No.

6271-21-2

SMILES

O[[email protected]]1[[email protected]]2([H])[[email protected]]3([H])N(CC[[email protected]]3([H])C[[email protected]@H]1O)CC4=CC(OCO5)=C5C=C24

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Dihydrolycorine
Cat. No.:
HY-N2403
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