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Cat. No.: HY-100965R

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Diphenyleneiodonium chloride (Standard)

Name: Diphenyleneiodonium chloride (Standard)
Brand: MedChemExpress
SKU: HY-100965R
Availability: PreOrder

(Synonyms: DPI (Standard))

Diphenyleneiodonium chloride (Standard) is the analytical standard of Diphenyleneiodonium chloride (HY-100965). This product is intended for research and analytical applications. Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM. Diphenyleneiodonium chloride selectively inhibits intracellular reactive oxygen species.

For research use only. We do not sell to patients.

CAS No.: 4673-26-1
Formula: C₁₂H₈ClI
Molecular Weight:314.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Diphenyleneiodonium chloride (Standard) Chemical Structure

CAS No.: 4673-26-1

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 4673-26-1
Molecular Weight 314.55
Formula C₁₂H₈ClI
SMILES

C12=CC=CC=C1C3=CC=CC=C3[I+]2.[Cl-]
Synonyms

DPI (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Suzuki H, et al. The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor. Am J Physiol Cell Physiol. 2014 Aug 15;307(4):C384-94. [Content Brief]

[2]. He YF, et al. Diphenyleneiodonium protects preoligodendrocytes against endotoxin-activated microglial NADPH oxidase-generated peroxynitrite in a neonatal rat model of periventricular leukomalacia. Brain Res. 2013 Jan 25;1492:108-21. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Diphenyleneiodonium chloride (Standard)

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Diphenyleneiodonium chloride (Standard)