Argireline acetate
Based on 2 publication(s) in Google Scholar
Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity.
For research use only. We do not sell to patients.
- CAS No.: 2484708-86-1
- Formula: C36H64N14O14S
- Molecular Weight:949.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Argireline acetate
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Biological Activity
The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2484708-86-1
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Molecular Weight 949.04
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Formula C36H64N14O14S
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Synonyms
Acetyl hexapeptide-3 acetate; Acetyl hexapeptide-8 acetate
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Sequence
N-acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2
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Sequence Shortening
Ac-EEMQRR-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Proc Natl Acad Sci U S A
Methionine-specific nonreversible bioconjugation: Advancing precision protein modification. [Abstract]2026 Feb 17;123(7):e2519038123. PMID: 41665996 -
Purity & Documentation
References
[1]. Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24(5):303-10. [Content Brief]
[2]. Grosicki M, et al. The study of cellular cytotoxicity of argireline - an anti-aging peptide. Acta Biochim Pol. 2014;61(1):29-32. [Content Brief]
[3]. Wang Y, et al. The anti-wrinkle efficacy of Argireline. J Cosmet Laser Ther. 2013 Aug;15(4):237-41. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Argireline acetate Related Classifications
HY-P0033A Related Classifications
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